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Testosterone deficiency can also contribute to a reduction in general quality of life, tiredness, depression, headaches, cognitive problems, osteoporosis and sarcopenia. Other contributory factors which should be taken into account when assessing women with these symptoms include psychosexual, physical, iatrogenic and environmental. This can lead to a number of distressing sexual symptoms such as low sexual desire, arousal and orgasm. 3 What is the impact of testosterone deficiency? Testosterone also maintains normal metabolic function, muscle and bone strength, urogenital health, mood and cognitive function. Testosterone contributes to libido, sexual arousal and orgasm by increasing dopamine levels in the central nervous system. surgical and medical menopause and premature ovarian insufficiency when testosterone production decreases by more than 50%. Loss of testosterone is particularly profound after iatrogenic i.e.
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Testosterone levels naturally decline throughout a woman’s lifespan. Some of the effects are direct and some due to peripheral conversion to estrogen by aromatase. androstenedione and half from the adrenal glands e.g. Approximately half of endogenous testosterone and precursors are derived from the ovaries e.g. This represents three to four times the amount of estrogen produced by the ovaries. Healthy young women produce approximately 100 – 400 mcg per day. Testosterone is an important female hormone.